David J. Graves

Department of Chemical Engineering, University of Pennsylvania

Graphic from Penn Technology News, Learning the Cell's Secrets with DNA Microchips

The parallelism, economy, and speed that electrical engineers have enjoyed by integrating circuits on silicon chips are beginning to impact the wet chemistry laboratory, particularly in the biological and medical sciences. Photolithography and other technologies from microelectronics promise decreases in the costs associated with reagents, labor, and waste production. Such devices also are ideally matched to the enormous analytical and data demands of genomics. Work by the speaker and his collaborators in microarray preparation and analysis will be discussed, and other approaches will be mentioned.